北大研究員成功構建出有料的細胞

<p class="MsoNormal"><span style="mso-spacerun:'yes';font-family:宋體;mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;mso-bidi-font-family:'Times New Roman';font-size:9.0000pt;mso-font-kerning:1.0000pt;"><font face="宋體">研討人員花了一年多的時刻來調整化合物組合，直到他們</font>zui<font face="宋體">終發現一個組合可以生成重編程前期的一些細胞。但這些細胞依然缺乏多能性標志基因。經過增加 </font><font face="Calibri">DZNep </font><font face="宋體">，一種已知可促成晚期重編程階段的化合物，他們</font><font face="Calibri">zui</font><font face="宋體">終得到了完全重編程的細胞，但數量非常的少。</font></span><span style="mso-spacerun:'yes';font-family:宋體;mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;mso-bidi-font-family:'Times New Roman';font-size:9.0000pt;mso-font-kerning:1.0000pt;"><o:p></o:p></span></p> <p class="MsoNormal"><span style="mso-spacerun:'yes';font-family:宋體;mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;mso-bidi-font-family:'Times New Roman';font-size:9.0000pt;mso-font-kerning:1.0000pt;"><font face="宋體">隨后，研討人員又找到了另一個化合物將功率提高了</font> 40 <font face="宋體">倍。</font><font face="Calibri">zui</font><font face="宋體">終，使用 </font><font face="Calibri">7 </font><font face="宋體">個化合物組合的混合物，研討小組讓 </font><font face="Calibri">0.2% </font><font face="宋體">的細胞發生了轉化&mdash;&mdash;與選用規范 </font><font face="Calibri">iPS </font><font face="宋體">技術的成果適當。</font></span><span style="mso-spacerun:'yes';font-family:宋體;mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;mso-bidi-font-family:'Times New Roman';font-size:9.0000pt;mso-font-kerning:1.0000pt;"><o:p></o:p></span></p> <p class="MsoNormal"><span style="mso-spacerun:'yes';font-family:宋體;mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;mso-bidi-font-family:'Times New Roman';font-size:9.0000pt;mso-font-kerning:1.0000pt;"><font face="宋體">經過將這些細胞導入到發育小鼠胚胎中，該研討小組證明它們具有多能性。在動物體內，</font> CiPS <font face="宋體">細胞生成了一切重要的細胞類型，包含肝臟、心臟、腦、皮膚和肌肉。</font></span><span style="mso-spacerun:'yes';font-family:宋體;mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;mso-bidi-font-family:'Times New Roman';font-size:9.0000pt;mso-font-kerning:1.0000pt;"><o:p></o:p></span></p> <p class="MsoNormal"><span style="mso-spacerun:'yes';font-family:宋體;mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;mso-bidi-font-family:'Times New Roman';font-size:9.0000pt;mso-font-kerning:1.0000pt;">&ldquo;一直以來人們總想知道，小分子是否可以代替一切的因子。這篇論文證明它們確實可以。研討 <font face="Calibri">CiPS </font><font face="宋體">細胞可以讓我們深化地了解重編程機制，&rdquo;</font><font face="Calibri">Whitehead</font><font face="宋體">生物醫學研討所細胞生物學家 </font><font face="Calibri">Rudolf Jaenisch </font><font face="宋體">說。</font><font face="Calibri">Jaenisch </font><font face="宋體">是批構建出 有料細胞的科研人員之一。</font></span><span style="mso-spacerun:'yes';font-family:宋體;mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;mso-bidi-font-family:'Times New Roman';font-size:9.0000pt;mso-font-kerning:1.0000pt;"><o:p></o:p></span></p> <p class="MsoNormal"><span style="mso-spacerun:'yes';font-family:宋體;mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;mso-bidi-font-family:'Times New Roman';font-size:9.0000pt;mso-font-kerning:1.0000pt;"><font face="宋體">上海酶聯科技有限公司年中特賣會開端啦，全場試劑盒產品一概</font>zui<font face="宋體">賤價出售，概況歡迎教師和同學們來電咨詢或咨詢在線人員！</font></span><span style="mso-spacerun:'yes';font-family:Calibri;mso-fareast-font-family:宋體;mso-bidi-font-family:'Times New Roman';font-size:9.0000pt;mso-font-kerning:1.0000pt;"><o:p></o:p></span></p>